University of Calgary Web Site    THE YOUNG LABORATORY
The Southern Alberta Cancer Research Institute, and the Departments of Biochemistry & Molecular Biology and Oncology

Recent Publications


Loewith, R., A. Hubberstey, and D. Young. 2000. Skh1, the MEK component of the Mkh1 signaling pathway in Schizosaccharomyces pombe. J. Cell Sci. 113:153-160. download (pdf format)

Loewith, R., M. Meijer, S. Lees-Miller, K. Riabowol, and D. Young. 2000. Three yeast proteins related to the candidate human tumor suppressor p33ING1 are associated with histone acetyltransferase activities. Mol. Cell. Biol. 20:3807-3816. download

Loweith, R., J. S. Smith, M. Meijer, T. J. Williams, N. Bachman, J. D. Boeke, and D. Young. 2001. Pho23 is associated with the Rpd3 histone deacetylase and is required for its normal function in regulation of gene expression and silencing in Saccharomyces cerevisiae. J. Biol. Chem. 276:24068-24074. download

Scott, M., P. Bonnefin, D. Vieyra, F. M. Boisvert, D. Young, D. P. Bazett-Jones, and K. Riabowol. 2001. UV-induced binding of ING1 to PCNA regulates the induction of apoptosis. J. Cell Sci. 114:3455-3462. download

Meijer, M., F. Karimi-Busheri, T. Y. Huang, M. Weinfeld, and D. Young. 2002. Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe. J. Biol. Chem. 277:4050-4055. download

Vieyra, D., R. Loewith, M. Scott, P. Bonnefin, F. M. Boisvert, P. Cheema, S. Pastyryeva, M. Meijer, R. N. Johnston, D. P. Bazett-Jones, S. McMahon, M. D. Cole, D. Young, and K. Riabowol. 2002. Human Ing1 proteins differentially regulate histone acetylation. J. Biol. Chem. 277:29832-29839. download

Huang, T. Y., N. A. Markley, and D. Young. 2003. Nak1, an essential GC kinase regulates cell morphology and growth in Schizosaccharomyces pombe. J. Biol. Chem. 278:991-997. download

Huang, T. Y., M. Renaud-Young, and D. Young. 2005. Nak1 interacts with Hob1 and Wsp1 to regulate cell growth and polarity in Schizosaccharomyces pombe. J. Cell Sci. 118:199-210. download

Colina, A.R., and D. Young. 2005. RAF60, a novel component of the RPD3 histone deacetylase complex required for RPD3 activity in Saccaromyces cerevisisae. J. Biol. Chem. 280:42552-42556. download


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