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The UCDNA Services facility was established in 1985, when Richard Pon relocated from a position with Bio Logicals at McGill University to the University of Calgary. This was only the second core faciilty (after peptide sequencing)  to be created in the Faculty of Medicine. Originally called the Regional DNA Synthesis Laboratory, the new service used one of the first automated DNA synthesizers (an ABI 380A three column synthesizer). At that time, such technology was expensive and not readily available and the new facility was soon providing synthetic oligonucleotides to researchers across Canada.

In 1992, automated DNA sequencing was introduced as a core service and the facility was renamed University Core DNA Services or simply UCDNA Services to accomodate this expansion. Our first instrument was an Applied Biosystems 373A sequencer with 36 lane (sample) capacity capable of reading 300 bases of sequence per day (10.8kb/day). Over the years, the sequencing instrumentation has upgraded several times and now a high-throughput 96-capillary Applied Biosystems 3730xl sequencer with 1,000 base reads and over 1 million bases/day capacity is used. Multi-user shared core facilities are the most efficient method for maximizing the utilization of specialized instrumentation. As a member laboratory in our Faculty's new Centre for Advanced Technologies, the University Core DNA Services facility works with other technology intensive researchers to increase the availability of various "Enabling Technologies" across a broad spectrum of disciplines.

In 2011, in partnership with the Alberta Children's Hospital Research Institute (ACHRI), next-generation DNA sequencing services were implemented. A full range of NGS services are now available to all University of Calgary researchers through the Genomics and Bioinformatics Platform at