University Core DNA Services
We are a multi-user core facility and provide custom oligonucleotide (DNA and RNA) synthesis and automated DNA sequencing and fragment analysis services to both academic and commercial researchers. These services are not restricted to the University of Calgary and are also available to external academic and commercial researchers.
DNA Synthesis, to 120 bases long
RNA Synthesis, including 2'-O-methyl RNA and 2'-O-fluoro RNA nucleosides, and siRNA (RNAi)
Locked Nucleic Acids (LNA)
Phosphorothioate antisense oligonucleotides
Dye labeled and dual-labeled oligonucleotides
We are specialists in nucleic acid chemistry and solid-phase synthesis and regularly prepare a wide range of unusual or highly modified oligonucleotides that are difficult or very expensive to obtain from other sources.
Applied Biosystems 3730XL 96 capillary sequencer
DNA sequencing from a wide range of templates for small and large-scale projects
Wide range of fragment analyses including SNPs, microsatellites, AFLP, T-RFLP, SSCP, relative fluorescent quantitation, mapping, and fingerprinting
Use our online dnaLIMS system for submitting sequencing requests and retrieving data at http://www.sequencing.ucalgary.ca/
We are a member laboratory in the Association of Biomolecular Resource Facilities and the Centre for Advanced Technologies at the University of Calgary.
UCDNA Services, Faculty of Medicine, University of Calgary
3350 Hospital Drive NW, Calgary, AB, Canada T2N 4N1
Synthesis Lab: tel. 403-220-4277; e-mail dnalab [at] ucalgary [dot] ca
Sequencing Lab: tel. 403-220-4503; e-mail dnaseq [at] ucalgary [dot] ca