University of Calgary
UofC Navigation

Dr. Margaret Kelly

Margaret Kelly

Associate Professor

University of Calgary, Cumming School of Medicine

 

Departments:

Pathology and Laboratory Medicine

Physiology & Pharmacology

 

Telephone number: 403 220.6870

Fax number: 403 210.7944

Email address:  mmkelly@ucalgary.ca

Primary Institute:    Snyder Institute for Chronic Diseases

 

About Dr. Kelly 

I am a Clinician-Scientist (Pulmonary Pathologist), with an interest in chronic lung diseases, specifically inflammatory and remodeling aspects. My lab focuses on asthma and interstitial lung diseases such as Hypersensitivity Pneumonitis (HP), Idiopathic Pulmonary Fibrosis (IPF), and autoimmune lung disease. We have a mouse model of severe neutrophilic asthma with airway remodeling and a model of chronic pulmonary fibrosis in which the pattern of fibrosis is similar to that seen in chronic HP and IPF. As part of the airway inflammation group, my lab is also involved in sputum and biopsy based studies in asthma and COPD.
Techniques in which my lab specializes include:

  • Administration of specific volumes of reagents into the mouse lung, using the Penn-Century Micro-sprayer. This technique allows for very accurate reliable administration of reagents by aerosol, which can be repeated as many times as required. The aerosol is evenly distributed throughout the lung fields.
  • Laser Capture Micro-Dissection and Real-Time PCR
  • Histology, immunohistochemistry, immuno-fluorescence and histochemistry
  • Electron Microscopy
  • Induced Sputum analysis 

AIRG Histology Services

Keywords:

Anatomical Pathology, Airway Remodeling, Pulmonary Pathology, Airway Inflammation, Interstitial Lung Disease, Myofibroblasts, Fibrosis, Ultrastructure, Immunology, Tissue Microdissection

 

Lab Manager:

Carol Gwozd, Medical Lab Technologist
cgwozd@ucalgary.ca
Phone number: 403 220.4751

Stephanie Chan, Lab Manager  snthe@ucalgary.ca

 

Administrative Assistant:

Tiziana (Tiz) Reiter
cyron@ucalgary.ca
Phone number: 403.210.6766