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Biomedical Engineering BMEN

Instruction offered by members of the Schulich School of Engineering and Kinesiology.

Associate Dean (Academic & Planning) - R. Brennan

Director, Centre for Bioengineering Research and Education - J. Ronsky

Biomedical Engineering 103 Q(20 hours)

(formerly Biomedical Engineering 003)

Health Care Management

Factors in modern health care provision and role of Biomedical engineering, economic and social constraints, methods for determining efficacy of treatment (outcome measures), assessment of life quality, provision and control of services, methods for determining local, national and global needs, importance of standards, quality control and measurement, effects of population demographics, historical developments and models of welfare provision.

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Biomedical Engineering 105 Q(20 hours)

(formerly Biomedical Engineering 005)

Introduction to Biomedical Engineering Research

Topics in Biomedical engineering, including scientific process, technical reports, research thesis, development of work plans, safety issues, biostatistics, ethics, career opportunities in Biomedical engineering, entrepreneurship, technology transfer, presentation skills. Some topics will be presented by guest lecturer, as appropriate. Student grade is based upon written and oral assignments.

Prerequisites: Biomedical Engineering 103, 309, 319, and 327.

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Senior Courses

Biomedical Engineering 309 H(3-3/2)

Anatomy and Physiology for Engineers

Physiological terminology and anatomical planes of reference; cell biology and physiology; includes structure and function of musculoskeletal, cardiac, nervous, gastrointestinal and respiratory tissues and systems; diseases and disorders of those systems; design constraints for bioengineering products.

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Biomedical Engineering 319 H(3-1.5T)

Applied Statistics for the Experimental Sciences

Presentation and description of data, introduction to probability theory, Bayes theorem, discrete and continuous probability distributions, estimation, sampling distributions, tests of hypotheses on means, variances and proportions, simple linear regression and correlation, multivariate analysis, power calculations and statistical significance for study design, non-parametric statistical tests, analysis of variance, additional models of regression analysis. Applications are chosen from bioengineering examples.

Prerequisites: Applied Mathematics 219.

Note: Credit for both Biomedical Engineering 319 and Engineering 319 will not be allowed.

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Biomedical Engineering 327 H(3-1T-3/2)

Electrical Circuits for Biomedical Engineers

Definition of linear elements, independent and dependent sources, sign conventions; basic circuit laws, simple resistive circuits; node and mesh analysis. Thevenin, Norton and other theorems; inductance and capacitance. AC circuit analysis, impedance, admittance, phasor diagrams; average and effective values of waveforms, real, reactive and complex power, power calculations; mutual inductance, ideal transformer, introduction to balanced three-phase circuits, power calculation in three-phase circuits. The tutorial and laboratory will introduce basic principles of sensors and measurement in a biomedical context. Includes signal amplification and filtering and analog-to-digital conversion.

Prerequisites: Physics 259.

Note: Credit for both Biomedical Engineering 327 and any of Engineering 325, Electrical Engineering 329 or 341 will not be allowed.

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Biomedical Engineering 405 H(3-1T-2)

Biological Tissue and System Mechanics

To understand the constitutive and structural behaviour of complex biological tissue: mechanical and electro-chemical properties of biological tissues, nonlinear and time-dependent behaviour, functional adaptation to load, multi-phasic materials, anisotropic and composite materials, structural and micro-structural behaviour, hierarchical modelling from system to tissue to cell, failure theories.

Prerequisites: Engineering 317, Biomedical Engineering 309.

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Biomedical Engineering 407 H(3-1T-2)

Cell Culture and Tissue Engineering

Mammalian cell culture, including nutrient metabolism, growth kinetics and scale up to bioreactors. Cell adhesion, cell aggregation, cell motility. Forces on cells, stress and strain, fluid shear. Mass transfer in tissues, extra-cellular matrix and tissue microenvironments, biomaterials, artificial organs. Therapeutic molecule production from genetically engineered cells.

Prerequisites: Biomedical Engineering 309.

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Biomedical Engineering 409 H(3-1T -2)


The generation, transmission, and measurement of electrical events generated by the excitable cells which compose the heart, brain, and muscle. Starting with the behaviour of ions in solution, a description of biologically generated electricity is built up to ultimately relate cellular activity to body surface potentials as measured by the electrocardiogram and electroencephalogram. Equivalent electrical circuit representations of biological structures are derived. Physiology specific to the organ being studied will be given.

Prerequisites: Chemistry 209, Biomedical Engineering 309, 327.

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Biomedical Engineering 500 M(1-8)

Biomedical Engineering Research Thesis

A directed studies research project worth three half-course equivalents in an area of interest, directed by a project advisor/faculty member within the faculties of Engineering, Kinesiology, Science or Medicine. Topics in Biomedical engineering will be covered. The project involves understanding of scientific process and application to identification of research project purpose, review of literature, development and description of methods, presentation of results and discussion of findings. Projects may involve experimental, analytic or computer modelling. Pre-session study is required.

Prerequisites: Final-year standing in the Engineering program of choice.

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Biomedical Engineering 501 H(1-2)

Biomedical Engineering Project

A directed studies project worth one half-course equivalent in an area of interest, supervised by a project advisor/faculty member within the faculties of Engineering, Kinesiology, Medicine, or Science. The project involves research of a particular product or process relevant to biomedical engineering, review of literature, review of patents and/or market, and justification for the selection of the medical technology, technique, or therapy. A final report and presentation are required. Typical project topics may include medical devices, cell based therapies, surgical techniques, diagnostic devices, biosensors, analysis software, or models. Pre-session study is required.

Prerequisites: Final-year standing in the Engineering program of choice.

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Biomedical Engineering 509 H(3-2)

(Geomatics Engineering 509)

Introduction to Biomedical Imaging and Applications

Principles of various imaging modalities used in Biomedical engineering applications, including CT, MRI, ultrasound, PET, SPECT. Introduction to basic image processing tools for image filtering, enhancement, feature extraction, recognition and 3-D reconstruction. Integration of different imaging modalities.

Prerequisites: Applied Mathematics 307 and one of Engineering 335, Computer Engineering 339, Civil Engineering 337 or Mechanical Engineering 337.

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Biomedical Engineering 511 H(3-2)

Biomaterials and Biocompatibility

Basic chemical and mechanical properties of biological and synthetic materials and their role in biological system health, dysfunction, and repair. Role of microstructure, material properties, and biocompatibility aspects in selection of biomaterials for medical or industrial applications. Incorporation of biomimetic concepts in material design. Topics may include artificial and tissue engineered products, implants, prostheses, biofilms, biosensors, and foreign body response.

Prerequisites: Biomedical Engineering 309 and one of 405 or 407.

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Biomedical Engineering 513 H(3-2)

Photogrammetric Techniques for Reconstruction and Manipulation of Biomedical Data

Photogrammetric techniques for biomedical applications; image acquisition, camera calibration, bundle adjustment, conventional and x-ray stereo imagery, accurate geometric measurements; and 3D reconstruction from 2D imagery. The course will also introduce the skills required for computer-based analysis, modelling, manipulation, visualization, reconstruction, pattern recognition, analysis, and diagnosis of biomedical data. Interactive 2D and 3D viewing of biomedical data, 3D views with correlated multi-planar 2D slice views, and 3D visualization.

Prerequisites: Engineering 233, Applied Mathematics 217, Biomedical Engineering 319.

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Biomedical Engineering 515 H(3-2)

BioengineeringSystems Physiology Modelling

Concepts from systems and control theory applied to physiological and biological systems. Feedback loops and stability. Parameter sensitivity analysis and parameter estimation techniques. Use of quantitative model-based approaches for integrative analysis of physiological and biological functions. Examples span a wide range from nervous system control of organ systems, such as autonomic control of heart rate and blood pressure, to "genetic circuits" describing how different gene products (proteins) interact to carry out cellular functions.

Prerequisites: Applied Mathematics 307.

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Biomedical Engineering 517 H(3-2)

Biomedical Device Development

Identification and categorization of current and near-term opportunities for biomedical devices. Introduction to the biomedical product development cycle. Categorization and requirements of biomedical devices from a regulatory perspective. Differences between the start-up and corporate environments. Financing of new product initiatives. Treatment of intellectual property and patents. Biomedical industry specific case studies will be presented.

Prerequisites: Final-year standing in the Engineering program of choice.

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Biomedical Engineering 519 H(3-2)

Special Topics in Biomedical Engineering

Current topics in Biomedical engineering.

Prerequisites: Consent of the BMES Director or designate.


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Graduate Courses

Biomedical Engineering 601 H(3-0)

Fundamentals of Biomedical Engineering

An introduction to biology, biochemistry, anatomy, physiology, engineering fundamentals, and biostatistics for biomedical engineers. Detailed discussion on bioengineering and biomedical engineering, including current local and international research and industry, emphasis on local strengths.

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Biomedical Engineering 603 H(3-0)

Frontiers of Biomedical Engineering

An introduction to research in biomedical engineering, experimental design, preparation and review of research proposals, technical (oral and written) communication to diverse audiences, obtaining employment in industry, academia.

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Biomedical Engineering 605 Q(1.5S-0)

Research Seminars in Biomedical Engineering

Reports of studies of the literature or of current research.


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Biomedical Engineering 607 Q(1.5S-0)

Research Seminars in Biomedical Engineering

Reports of studies of the literature or of current research.


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Biomedical Engineering 609 H(3-3/2)

Anatomy and Physiology for Biomedical Engineers

Advanced instruction on human skeletal structure, types of connective tissues, structure of joints, muscle and organ structure and function, cardiac physiology, blood properties and flow, introduction to autonomous nervous system, and disorders of the musculoskeletal system. Other topics will be covered dependent on the interests of the instructor and students.

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Biomedical Engineering 619 H(3-1)

Special Problems in Biomedical Engineering

Designed to provide graduate students, especially at the PhD level, with the opportunity of pursuing advanced studies in particular areas under the direction of a faculty member.


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