Shedding light on brain oxygenation
Summary
The main purpose of this study is to use Near-Infrared (NIR) light to determine the prevalence of low brain oxygen in multiple sclerosis patients and controls, and to determine whether low brain oxygen is constant or changes over time. We also want to determine whether low brain oxygen relates to clinical disability and/or relapse in MS patients.
NIR light is a non-invasive imaging technique that can be used to measure brain oxygenation. NIR Spectroscopy (NIRS) utilizes low intensity light, so there is no risk of side effects or complications. For this reason, NIRS is frequently used to monitor patients in the Intensive Care Unit. Brain oxygenation has been shown by our group to be reduced in multiple sclerosis (MS) patients compared to control subjects.
Eligibility
Eligible gender: Male, Female, Transgender, Other
Eligible ages: 18 to 65
Accepts healthy participants: Yes
Inclusion criteria:
Age 18-65
Men and women
Clinical diagnosis of MS
Non-smoker (nicotine or Marijuana)
Selection criteria Controls:
Age 18-65
Men and women
Non-smoker (nicotine or Marijuana)
No recent systemic infection
Otherwise healthy
No history of cardiovascular/vascular disease
Participate
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Additional information
Contact information
If you are interested in participating in this study, or if you would like more information, please contact us at 4032208130
Principal investigator:
Jeffrey Dunn
Clinical trial:
No
REB-ID:
REB19-1105