BRAIN Study
Summary
The purpose of this study is to try and understand how the adolescent brain responds to pain. The first part of the study involves teens filling out an online questionnaire, which asks about pain, sleep and mental health. They will receive a $10 gift card for answering this questionnaire.
One week later, we will have the teen come to the Alberta Children's Hospital. Using a device that applies thermal heat, we will establish their threshold for low, medium and high heat on their forearm. We will then apply 3 creams to their forearm: 1) one will enhance sensitivity to pain; 2) one will have no effect on pain; and 3) one will decrease sensitivity to pain. We will test their responses to the creams both outside and inside the MRI. Transportation to and parking at the hospital will be reimbursed via gift card. Teens will receive an additional $20 gift card and pictures of their brain to thank them for participating in this study.
Eligibility
Eligible gender: Male, Female, Transgender, Other
Eligible ages: 14 to 18
Accepts healthy participants: Yes
Inclusion criteria:
Inclusion criteria include:
1) Healthy adolescents aged 14-18 years
2) Ability to read and speak English
3) No neurodevelopmental disorders
4) No neuropsychiatric disorders
5) No neuropsychotropic medication
6) No chronic medical conditions
Exclusion criteria:
Potential participants with any of the following will be excluded:
1) History of chronic pain
2) Significant head trauma
3) Diagnosed neurological, developmental, or psychiatric disorder
4) Alcohol or substance use problem
5) Major chronic medical disease
6) Pregnancy
7) Contraindications to MRI (e.g., braces, claustrophobia).
Participate
Fill out the following form if you want to participate in this research
Collection of personal information
Your personal information is collected under
the authority of section 33(c) of the Freedom of Information and Protection of Privacy Act. If
you have any questions about the collection or use of this information, please visit our
Access to Information page.
Additional information
Contact information
Dr. Jill Miller Assistant Professor, Neuroscience Department of Anesthesiology, Perioperative & Pain Medicine Cumming School of Medicine, University of Calgary
Principal investigator:
Jillian Miller
Clinical trial:
No
REB-ID:
REB22-1633