Attention in Early Childhood: Risk Factors Including Preterm Birth and Turner Syndrome and Intervention Response
Summary
Children who are born very preterm are at increased risk for problems with attention. Attention skills mature rapidly in young children and are especially important as children start school.
In this study we will use brain MRI and measures of attention to find brain differences that may put children born early at greater risk for attention difficulties.
Eligibility
Eligible gender: Male, Female
Eligible ages: 4 to 6
Accepts healthy participants: Yes
Inclusion criteria:
Children born very preterm (24- 32 weeks and/or < 1000g), children born moderately preterm (33-36 weeks) and full term (>=37 weeks)
• A parent and the child must be fluent in English in order to participate.
Exclusion criteria:
• MRI contraindications (e.g. metallic implants)
• FIQ > 2 standard deviations below the mean based on clinical assessment;
• bilateral blindness with corrected visual acuity <20/200 in the better eye;
• seizure disorder;
• bilateral neurosensory hearing loss,
• cerebral palsy of any type or severity
Note: co-morbid diagnoses such as ASD. ADHD diagnosis will not be exclusionary; symptoms will be assessed, and participants will be excluded if they take stimulant medication.
2) Girls with Turner Syndrome
Inclusion criteria :
• Diagnosis of classic or mosaic TS based on genetic test
Exclusion criteria:
• MRI contraindications
Participate
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Additional information
Contact information
Signe Bray
Principal investigator:
Signe Bray
Clinical trial:
No
REB-ID:
REB18-0716