CVOT SYNCHRONIZE

Summary

The purpose of this trial is to find out whether an experimental drug provides cardiovascular protection or does not increase risk to the heart and blood vessels when used in patients living with overweight or obesity. We want to look at this in patients living with overweight or obesity who have risk factors for cardiovascular disease or established cardiovascular or chronic kidney disease. To do this we will look at the effect on the heart and blood vessels by counting the number of cardiovascular events (e.g., heart attack or stroke) that happens in people during this study. Participants will be placed on a weight loss and physical activity regimen and change in body weight will be tracked.