vision; retinal structure, circuitry, and function; myopia, visual control of eye growth and refraction; inherited disorders of retinal structure and We use digital microscopy and immunohistochemistry to identify circuit elements in the retina, and the optokinetic response (OKR) to quantify retinal contrast sensitivity and spatial acuity, in small-animal models.
We study myopia (near- or short-sightedness) and astigmatism in young chickens - using diffusers and lenses to induce changes in eye growth; intraocular injection of stimulators and inhibitors of retinal singling systems, to probe the underlying neural image-processing mechanisms; and slit retinoscopy and A-scan ultrasound to measure the changes in refractions and axial length of the eye.
In collaboration with Prof. Torben Bech-Hansen, we use microscopy, immunohistochemistry, and OKR testing - as well as genetic manipulation of the genome - to study a mouse model of X-linked congenital stationary night blindness (CSNB2A).
This supervisor is currently seeking students.
Seeking MSc student for degree in Neuroscience, to start in September 2017 or January 2018. Undergraduate Honours degree preferred (e.g.: BHSc - BioMedical, or BSc - Neuroscience). Must be psychologically and ethically able to handle, operate on, euthanize, and dissect 1-2 week old chickens. Prior experience in planning, carrying out, analyzing, and presenting results of wet-lab experiments on small animals will be an asset.
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