Structural Biology My research focuses on using the tools of structural biology to understand how enzymes function in the human body. We purify human and bacterial enzymes produced in E. coli to investigate their activities and study their structures. Our primary tool to study their structures is X-ray crystallography. We crystallize the enzymes and ship our crystals to synchrotrons in Canada or the USA where we collect diffraction data. From these data we interpret how the enzymes work.
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