PhD in Biology with Specialization in Biochemistry
Carleton University, Ottawa, Canada
Areas of Research
- Vascular smooth muscle biology
Research activities focus on signal transduction mechanisms (i.e., zipper-interacting protein kinase & myosin phosphatase & smoothelin-like 1 protein) linked to the control of vascular smooth muscle contractility in health and disease. See- Scientific Reports (2019) 9(1):481; Microcirculation (2014) 21(3),249-58; Journal of Biological Chemistry, (2012) 287(43),36356-69; Journal of Biological Chemistry (2011) 286(42),36978-91 - Chronic inflammation
Research activities explore the structure and function of the NOD-like receptor proteins in sterile inflammation See: Cell Reports (2018) 25(6):1525-1536; Journal of Clinical Investigation (2018) 128(7):2894-2913; Nature Immunology (2016) 17(10),1176-86; Nature Medicine (2012) 18(4), 600-4; Gastroenterology (2010) 139(2),542-52 - Chemoproteomic drug discovery
Collaborative research employs mass spectrometry and proteomic strategies to identify therapeutic small molecules for the treatment of vascular disorders. See: Cell Chemical Biology (2018) 25(10)1195-1207; Scientific Reports (2016) 6,32118; Molecular Pharmacology (2016) 89(1),105-17; ACS Chemical Biology (2013) 8(12),2715-23
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