Ongoing Clinical Trials

STEP 10

STEP 10 Weight Loss Trial

STEP 10: Efficacy and Safety of Subcutaneous Semaglutide 2.4mg Once-Weekly in Subjects with Obesity and Prediabetes

STEP 10 is investigating the use of Ozempic in patients with obesity and prediabetes. This study will investigate if pre-diabetic patients with obesity who use this medication will lose weight, improve blood sugar, cholesterol, blood pressure and other measures of health. Patients will be required to attend clinic visits for basic measurements, bloodwork, and study drug dispensation.  Visits will occur every 4th week during dose escalation, and every 8th week during the maintenance phase.  End of treatment occurs at week 52, with follow up continuing to week 80.  Patients will receive health and lifestyle guidance, injection support, and study medication. There will be no costs to the patient to participate in this study. 

Have questions? Call Michelle 403-955-8117 or mahunter@ucalgary.ca

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PERL Skeletal Health Study

PERL Skeletal Health Study (Follow-up Study):

PERL Skeletal is a PERL follow-up study. The PERL Skeletal Study is being conducted to investigate the effects of Type 1 Diabetes on skeletal and bone health within a population in which kidney function is well known.This is an observational, multicenter, prospective, post-RCT (Randomized Control Trial) cohort study.

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REMIT-IDegLira

REMIT-IDegLira: Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes with IDegLira

Approximately 1 in 10 adults in Canada currently have diagnosed diabetes. Recent research suggests that it may be possible to reverse type 2 diabetes or put it into remission using intensive lifestyle therapy and short-term combination drug therapy with injectable insulin and oral diabetes medications. This trial will test whether a short treatment with a combined basal insulin degludec and Liraglutide (IDegLira), metformin, and lifestyle is able to achieve prolonged diabetes remission.

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Due to the COVID-19 Pandemic many clinical trials have been delayed. 

We are open for important research that provides medical care to patients living with chronic diseases. 

Please come back to this website as we will continue to update our active clinical trials page! 

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