John L. Wallace, PhD, MBA, FRSC
BSc (Queen’s), MSc (Queen’s), PhD (Toronto), MBA (Birmingham, UK)


 

 

 

 


Director, Farncombe Family Institute of Digestive Health Research
McMaster University
1200 Main Street West, HSC 3N9
Hamilton, Ontario, L8N 3Z5, Canada

Tel: 905-525-9140 ext 22591
Fax: 905-528-9862
E-mail:
wallacejohn@mcmaster.ca
Website:
http://farncombe.mcmaster.ca
 

Research

My major research interest is inflammation and the impact that it has on tissue injury and repair of injury.  Most of my work involves studies of inflammation and ulceration in the gastrointestinal tract, although I also have a long-standing interest in cardiovascular inflammation and platelet function.  I am particularly interested in identification of novel targets for anti-inflammatory therapies, and the subsequent development of such therapies.  I was a scientific co-founder of NicOx, a company based in France which is developing nitric oxide-releasing derivatives of several classes of drugs (see www.nicox.com).  More recently, I founded Antibe Therapeutics Inc., which has offices in Calgary and Toronto (see www.antibe-therapeutics.com) and is developing hydrogen sulfide-releasing derivatives of drugs for inflammatory bowel disease, arthritis, irritable bowel syndrome and endothelial dysfunction. 

Please note that I will consider applications from potential post-doctoral fellows for training positions in my laboratory.
 

View PubMed Listings for John L. Wallace

Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself? Physiol Rev. 2008 Oct;88(4):1547-1565.

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