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in the
Inflammation Research Network

Vaccine may treat deadly dysentery.
Millions of children in developing countries could eventually be saved by a vaccine being developed at the University of Calgary.
At least 100,000 people die and millions are sickened by amoebic dysentery every year.
Although most amoebas are harmless, one type ̶̶ Entamoeba histolytica ̶̶ attacks the stomach.
"Once you get an invasion into your intestines, you get this bloody diarrhea, and it doesn't end there," said Kris Chadee, a researcher at the UofC.
To read complete article click here

Congratulations to Dr. Samuel Asfaha on receiving a CAG/Procter & Gamble Resident Research Award under the supervision of Dr. Nathalie Vergnolle. This award is made possible through the partnership of Procter & Gamble Pharmaceuticals and the CAG.
Posted 13 April 2007

Eric Hyun (Dr. Vergnolle's laboratory) is the new "IRN Trainee Representative". He will report to the III trainee representative (Raza Zaher). Eric is a new point of contact for any IRN trainee who has comments or suggestions to improve IRN's training environment.
Posted 13 February 2007

Congratulations to Andrew Flynn (PhD student in Dr. Buret’s laboratory) and Manigandan Leijeune (PhD student in Dr. Chadee’s laboratory) on being awarded the student prize by the Canadian Association of Gastroenterology.
Posted 5 February 2007

Congratulations to Nicolas Cenac (Post-doc, Dr. Vergnolle's lab) and Catherine Ivory (PhD student, Dr. Chadee's lab) on receiving the best student prize at the Banff Inflammation Workshop held January 18-21, 2007 in Banff, AB.

Congratulations to Dr. Kristina K. Hansen (Dr. M. Hollenberg's lab in collaboration with Drs. Vergnolle and Sherman) winner of the Pfizer Post-doctoral Prize for best publications in a given year at the University of Calgary, Faculty of Medicine.
Dr. Hansen's work published in 2006, described both in a first-author PNAS manuscript and in a second-author JBC manuscript, has identified serine proteinases (trypsin-2 and tissue Kallikreins 5, 6 and 14) that can play roles in vascular and gastrointestinal diseases by regulating the G-protein-coupled receptor family of Proteinase-activated receptors (PARs 1, 2 and 4). In the PNAS paper, proof of principle is provided to indicate that the inhibition of the PAR-activating enzymes can prevent the development of infectious colitis. The work therefore has both therapeutic and theoretical implications for cardiovascular and gastrointestinal pathophysiology.
Hansen KK, S, Drherman PM, Cellars L, Andrade-Gordon P, Pan Z, Baruch A, Wallace JL, Hollenberg MD, Vergnolle N. A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8363-8.
Oikonomopoulou K, Hansen KK, Saifeddine M, Tea I, Blaber M, Blaber SI, Scarisbrick I, Andrade-Gordon P, Cottrell GS, Bunnett NW, Diamandis EP, Hollenberg MD.Proteinase-activated receptors, targets for kallikrein signaling. J Biol Chem. 2006 Oct 27;281(43):32095-112.

Posted 8 January 2007

It’s a GIRL!!
Our warmest wishes and congratulations go out to Nicolas & Claire Cenac on the birth of their daughter Mathilde. Mathilde was born Sunday, October 29th, 2006 at 5:00 p.m. weighing in at 5.5 pounds (2.5 kg) and is 19.6 inches (50 cm) long. Both mother and daughter are doing fine.

Posted 30 October 2006

Collaborative research between MIRG, the Neurovascular Inflammation Group, University of Glasgow, and the University of Paisley: 8th for ‘hits’ on world-wide web.

A recent article generated through this research 'Therapeutic promise of PAR2 antagonism in joint inflammation' has been ranked 8th in terms of number of 'hits' via world-wide web.

Kelso EB, Lockhart JC, Hembrough T, Dunning L, Plevin R, Hollenberg MD, Sommerhoff CP, McLean JS, Ferrell WR. Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation. J Pharmacol Exp Ther. 2006 Mar;316(3):1017-24.

Dr. Andre Buret received the 2007 Research Excellence Award from the Canadian Association of Gastroenterology. This prestigious prize represents the Association’s top Award.
Congratulations Andre!

Dr. John Wallace was awarded the 2007 Visiting Professorship Award from the Canadian Association of Gastroenterology. Another prize to add to John’s long list of well-deserved awards.    Well done John!

Posted 5 October 2006

Congratulations to Dr. Quentin Pittman on being awarded a University Professorship by the University of Calgary.

Posted 29 September 2006

Double honour for Dr. John Wallace.
Dr. Wallace is being awarded the 2006 Gaddum Memorial Award, from the British Pharmacological Society. He has also won the Senior Scientist Award of the Pharmacological Society of Canada, this is the Society's most prestigious award.

These awards recognize the important contributions he has made to the field of pharmacology.

Dr. Wallace will receive the 2006 Gaddum Memorial Award at the Society's Winter meeting which will be held at Oxford in December. He will receive the Senior Scientist Award on Friday, July 7 at IUPHAR2006 in Beijing.

Congratulations John on these outstanding achievements!
Posted 16 May 2006

Congratulations to Dr. John Wallace on being elected a Foreign Member of the Brazilian Academy of Sciences by the General Assembly held on March 9th, 2006.

This award recognizes Dr. Wallace's outstanding contributions to Brazilian science, through collaboration, contributions to conferences and mentorship of many young Brazilian scientists. Congratulations John on this prestigious honour!

Posted 14 March 2006

Congratulations to Dr. Nathalie Vergnolle on receiving the 2006 Masters Award for Basic or Clinical Research in Digestive Diseases, from the American Gastroenterological Association. This prestigious award recognizes investigators whose research has advanced the understanding of gastrointestinal disease. Nathalie will receive the award in May, at the Digestive Disease Week in Los Angeles.

Congratulations to Nathalie on this well-deserved international recognition of her research achievements - well done!

Posted 2 March 2006

Congratulations to Drs. Hongying Wang and Veronica Swystun, post-docs in Dr. MacNaughton's lab, on receiving 2-year CAG-CIHR-CCFC Fellowships. Congratulations also to Dr. Gary Martin, a post-doc in Dr. Wallace's lab, on receiving a 3-year CAG-CIHR-AstraZeneca Fellowship.

Posted 17 January 2006

Dr. Hongying Wang, a post-doc in Dr. MacNaughton's lab, was awarded the Biomol Young Investigator Award at the recent meeting on Eicosanoids & Other Bioactive Lipds in Cancer, Inflammation and Related Diseases, held in San Francisco Sept 11-14. Congratulations, Hongying, on this significant accomplishment!

Posted September 19, 2005

Our warmest wishes and congratulations go out to Renata Zanardo and her husband, Gordon Hamilton on the birth of their first child, Keefer Zanardo Hamilton. Keefer was born Wednesday, 15 June 2005 and weighed π kilos (3.141 kg).

Posted July 28, 2005

Congratulations to Dr. Quentin Pittman on being renewed as an AHFMR Medical Scientist. This is the 6th successive 5- year term of salary support that he has obtained from outside agencies. Outstanding achievement Quentin!

Posted May 20, 2005

Another prestigious Award for Dr. John L. Wallace!
Dr. Wallace will receive the "Leadership in Canadian Pharmaceutical Sciences Award" from the Canadian Society for Pharmaceutical Sciences. This award recognises the impact that his work has had on pharmaceutical science internationally. Congratulations John.

Posted April 21, 2005

Prestigious Award for Prof. John L. Wallace!
The selection committee for the "Masters Award in Gastroenterology" has recognized the career achievements of John in the field of Gastroenterology. John will be awarded this prestigious prize by the American Gastroenterology Association at the Digestive Disease Week conference to be held in Chicago (14-18 May 2005). This award reflects the tremendous contribution of Dr. John Wallace to digestive disease sciences and recognizes most appropriately the very unique and influential achievements of John in that field. Congratulations John on this well-deserved honour!

Posted March 17, 2005

Congratulations to Dr. Pierre-Yves von der Weid on receiving the "Warren Veale Award", for a year of outstanding performance in research scholarship, education and service by an Assistant Professor in the Department of Physiology & Biophysics.

Posted February 17, 2005

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