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All Our Babies Cohort

Submitted by mvekved on Tue, 07/12/2011 - 11:36am

Developing a unique research legacy to inform policy, practice, and health service planning to improve outcomes for Alberta's children

About the Cohort

Cohort: Recruitment of the cohort is completed with about 3,300 Alberta mothers and their babies. Mothers were recruited early in pregnancy.

Births: The first baby was born in August 2008, and the last was born in July 2011.

Research Objectives:

1. To understand women's pregnancy experiences

  • What are barriers and facilitators to accessing prenatal care? 
  • What proportion of Calgary women have poor mental health and social support? 
  • What impact does care have on women's well-being?

2. To predict preterm birth

  • Are there gene expression patterns at 18-22 weeks & 28-32 weeks of pregnancy that predict preterm birth?
  • What is the relative impact of genes and environment on the risk of preterm birth?

3. To understand what are the associations between gestational age and:

  • longitudinal trajectories of health and development during early childhood?
  • domain-specific development outcomes?

Data Collected to Date


Questionnaires (N~3,300)
(contact us for questionnaire copies)

  • <24 weeks gestation 
  • 32-36 weeks gestation
  • 4 months postpartum
  • 1 year postpartum
  • 2 years postpartum
  • 3 years postpartum
  • 5 years postpartum
Questionnaire content below.


Biological Samples (N~1,800)

  • Maternal Blood Samples
    • 18-22 weeks gestation
    • 28-32 weeks gestation
  • Cord Blood (after delivery)

Planned Follow-up Studies

Time frame: The follow-up began in 2011/12 when children were one year old and continued with questionnaires when children were two and three. The current follow-up questionnaire at age 5 is underway as the children begin to enter school.

Data to be collected: At each data collection point, women will complete questionnaires about child development, psychosocial health and parenting, and resource utilization (health services and other resources). Women will receive gift certificates for completing questionnaires and reminder phone calls if a questionnaire has not been returned.

Maintaining involvement: To keep women engaged in the study between questionnaires, we continue to distribute newsletters and greeting cards. This allows us to keep track of participants over time.

Linked studies: Existing biologic samples allow for research of mechanisms of the developmental origins of childhood and adult health.

What We're Learning Through the Cohort

Recruitment: Effective methods to recruit a population-based sample of pregnant women (see article)

Flu Vaccines: Rates and predictors of H1N1 and seasonal flu vaccines among pregnant women (see article)

Mother's Mental Health: Screening for postpartum depression in the prenatal period (see abstract on p.40)

Other Areas: Advice and weight gain in pregnancy; factors associated with paediatric vaccinations; prenatal care, mental health, and breastfeeding

Questionnaire Content