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Paul Kubes

Position: 

Professor and Director, Snyder Institute for Chronic Diseases

Address: 

Phone number(s):
Office: HRIC 4AA16 (403) 220-2705
Lab: HRIC 4A26A (403) 220-3012
Fax number: 403-270-7516

www.ucalgary.ca/paulkubeslab

Research Activities: 

Our laboratory uses cell biology approaches as well as mouse transgenic and knockout technology to delineate molecular mechanisms underlying the recruitment of leukocytes to sites of inflammation. Our particular interests have included the multi-step cascade of leukocyte recruitment which includes the proteins responsible for catching leukocytes and tethering them to the endothelium, as well as examining the proteins that contribute to leukocyte migration out of the vasculature. A sincere attempt is made to design human systems to test that mechanisms of action uncovered in mice have clinical relevance.

Key words describing research:

adhesion, microvasculatures, chemotaxis, selections, neutrophils, integrin, shock, ischemia, inflammation, toll-like receptors

Techniques used in your laboratory: 

adhesion, microvasculatures, chemotaxis, selections, neutrophils, integrin, shock, ischemia, inflammation, toll-like receptors

Research Funding: 
Alberta Cancer Foundation
Alberta Heritage Foundation for Medical Research
Alberta Innovates Health Solutions
Canadian Institutes of Health Research (CIHR)
Crohn's & Colitis Foundation of Canada 
Heart & Stroke Foundation of Canada (HSFC)
Administrative Assistant: 

Marlene Manson, mansonm@ucalgary.ca (403) 220-2705

Research Personnel: 
  • Derrice Knight, Lab Manager
  • Steve Johnson, PhD graduate student
  • Caroline Leger, Director Snyder Translational Lab
  • Woo-Yong Lee, Postdoctoral Fellow
  • Bjorn Petri, Postdoctoral Fellow
  • Florian Pilsczek, Postdoctoral Fellow
  • Sarah Pineau, Assistant Snyder Translational Lab
  • Rossana Urrutia, MSc graduate student
  • Chris Waterhouse, Postdoctoral Fellow
  • Hong Zhou, Postdoctoral Fellow
  • Connie Wong, Postdoctoral Fellow
  • Muhammad Asaduzzamen, Postdoctoral Fellow
  • Braedon McDonald, PhD Graduate Student
  • Candace Fahey, MSc graduate student
  • Zhiwen Guan, Postdoctoral Fellow
Degrees: 
  • Ph.D. (Doctor of Philosophy)