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Paul Kubes

Position: 

Professor and Director, Snyder Institute for Chronic Diseases

Address: 

Phone number(s):
Office: HRIC 4AA16 (403) 220-2705
Lab: HRIC 4A26A (403) 220-3012
Fax number: 403-270-7516

www.ucalgary.ca/paulkubeslab

Research Activities: 

Our laboratory uses cell biology approaches as well as mouse transgenic and knockout technology to delineate molecular mechanisms underlying the recruitment of leukocytes to sites of inflammation. Our particular interests have included the multi-step cascade of leukocyte recruitment which includes the proteins responsible for catching leukocytes and tethering them to the endothelium, as well as examining the proteins that contribute to leukocyte migration out of the vasculature. A sincere attempt is made to design human systems to test that mechanisms of action uncovered in mice have clinical relevance.

Key words describing research:

adhesion, microvasculatures, chemotaxis, selections, neutrophils, integrin, shock, ischemia, inflammation, toll-like receptors

Techniques used in your laboratory: 

adhesion, microvasculatures, chemotaxis, selections, neutrophils, integrin, shock, ischemia, inflammation, toll-like receptors

Research Funding: 
Alberta Cancer Foundation
Alberta Heritage Foundation for Medical Research
Alberta Innovates Health Solutions
Canadian Institutes of Health Research (CIHR)
Crohn's & Colitis Foundation of Canada 
Heart & Stroke Foundation of Canada (HSFC)
Degrees: 
  • Ph.D. (Doctor of Philosophy)
Research Personnel: 
  • Lori Zbytnuik, Lab Manager
  • Woo Yong Lee, Lab Technician
  • Michelle Willson, Lab Technician
  • Trecia Nussbaumer, Lab Technician
  • Justin Deniset, Postdoc Fellow
  • Bas Surewaard, Postdoc Fellow
  • Ajitha Thanabalasuriar, Postdoc Fellow
  • Jing Wang, Postdoc Fellow
  • Zhutian Zeng, Postdoc Fellow
  • Juha Korhonen, Postdoc Fellow
  • Liane Babes, PhD student
  • Jung Kim, PhD student
  • Pei Liew, PhD student
  • Rita Nguyen, PhD student
  • Keir Pittman, PhD student
  • Brittney Scott, PhD student
  • Ania Zuba, PhD student
  • Arpan Neupane, PhD student
  • Rachel Kratofil, PhD student
  • Grace Andonegui, Research Associate
Administrative Assistant: 

Elizabeth Saquibal

ejsaquib@ucalgary.ca

(403) 220-4132