Microbiology, Immunology & Infectious Diseases
Associate ProfessorMedicine Microbiology, Immunology & Infectious Diseases (MIID) Member, Infectious Diseases Research Group Address: Peter Lougheed Hospital Phone: (403) 943-4635 Fax: (403) 943-4017 Email: firstname.lastname@example.org
MD, University of Calgary
PhD, University of Calgary
Bacteria use a variety of mechanisms to ensure the success of their interaction with the host organism they infect. All living organisms eqire iron for a number of metabolic processes, and pathogenic bacteria have evolved a number of systems for acquiring this iron from the human host. In my laboratory we are studying the iron transport pathway(s) of the nosocomial opportunistic pathogen Stenotrophomonas (Xanthomonas) maltophilia , a gram negative pathogen of increasing importance in severely debiliated patients. We are examining iron transport as a potential virulence factor in this organism, and also as a potential antibiolotic delivery pathway.
In my role as an Infectious Diseases clinician, I deal with the problem of antibiotic resistance on a daily basis. We are initiating clinical studies to examine the development and spread of antibiotic resistance genes in the nosocomial setting, in particualr we are looking at the role of third generation cephalosporins in the selection of b-lactam resistance in the normal colonic flora.