Deborah Kurrasch
Professor
Departments of Medical Genetics, Biochemistry and Molecular Biology
PhD (Doctor of Philosophy)
Contact information
Research
Areas
- Developmental Genetics, Epilepsy, Model Organism, Novel Therapeutics
Reaearch Summary
We study hypothalamic programs that underlie neonatal/postnatal neuroendocrine signaling. The transition from a passive fetus to an independent neonate requires activation of a complex network of neuroendocrine genes. To understand what genes are critical during this late developmental time point, and if the postnatal age presents a window of vulnerability for environmental insult, we use the following tools:
- mice and zebrafish as model organisms
- immortalized hypothalamic cell lines
- microarray and NextGen sequencing
- molecular biology techniques
- targeted knockdown
- pharmacological manipulations