Raylene A. Reimer, PhD, RD
Associate Professor, Faculty of Kinesiology
Associate Professor, Faculty of Medicine, Department of Biochemistry & Molecular Biology
|1997-1999||Postdoctoral Fellow, Nestle Research Centre, Lausanne Switzerland|
|1997||PhD, Nutrition & Metabolism, Department of Agricultural, Food & Nutritional Science, University of Alberta|
|1993||BSc, Foods & Nutrition, University of Alberta|
There is widespread recognition that diet plays an important role in the incidence of many diseases including cardiovascular disease, diabetes, obesity, some cancers, osteoporosis and inflammatory conditions. The overall objective of my research is to couple the identification of genes involved in the pathogenesis of diabetes and obesity with nutrition-based strategies to prevent and/or treat these conditions. The specific aims of my current research program include:
Role of Intestinal Adaptation in Obesity. Using the genetically obese JCR:La-corpulent rat model we are examining the role of combination diets high in protein and fiber on intestinal adaptation, gut hormones involved in satiety, hepatic lipid synthesis and body weight regulation.
Regulation of GLP-1 (glucagon-like peptide-1) secretion. GLP-1 is a potent insulin secretagogue with high potential for the treatment of diabetes. We have established a molecular screening facility in which we are able to determine the role of specific nutrients and dietary compounds in triggering GLP-1 release. Using cell lines we can further explore the intracellular signaling pathways involved in GLP-1 secretion. Molecular biology techniques used by our lab include DNA microarrays and Real Time PCR.
Role of Diet Composition in Early Dietary Programming. It is now increasingly clear that dietary influences exerted early in life have long-term consequences, many of which are pathological. The goal of this work is to undertake basic research on how dietary patterns during growth and development affect physiological responses related to lipid and glucose metabolism in later life.
The long-term goal of our work is to identify novel nutritional therapies to prevent and treat chronic disease.
Recent Awards and Honours.
See Curriculum Vitae (PDF format) for a complete list.
|2007||Kinesiology Faculty Award of Excellence for Outstanding Contributions in Research|
|2002||URGC Travel Grant Award|
|2000-2001||Research Excellence Envelope Award, Alberta Innovation and Science|
College of Dietitians of Alberta
North American Association for the Study of Obesity
American Society for Nutritional Sciences
Canadian Society for Nutritional Sciences / Canadian Federation of Biological Societies
Canadian Diabetes Association
Canadian Society of Clinical Nutrition
|2007-2010||CIHR (Canadian Institutes of Health Research) Operating Grant Dietary Modulation of Integrated Gut Hormone Response to Manage Obesity. Principal Investigator: $291,224.|
|2008-2009||NSERC (Natural Sciences & Engineering Research Council) Operating Grant Influence of Nutrients on Developmental Programming of Metabolism. Principal Investigator: $32,500.|
|2008-2009||Canadian Centre for Functional Medicine Evaluation of Satiety Hormone Response with Dietary Fiber Supplementation in Obesity. Principal Investigator: $128,500. Research Contract.|
|2008-2009||Canadian Foundation for Dietetic Research The Impact of High Milk Product Intake during Weight Loss on Markers of Insulin Resistance. Co-Principal Investigator: $15,000. Co-Investigator: Kim Wagner Jones.|
|2008-2011||Agriculture Funding Consortium Effect of pulses as a source of fiber and resistant starch on satiety hormone production. Principal Investigator: $102,500.|
|2007-2009||University of Calgary Public Health InitiativeHealthy Uni: A campus-wide health promotion initiative driven by students and focused on wellness and the prevention of obesity and type II diabetes. Co-investigator: $160,000.|
|2004-2007||CIHR Operating Grant Regulation of Obesity with Intestinal Adaptation and Diet Composition. Principal Investigator: $296,700.|
|2003-2008||NSERC Operating Grant Metabolic Outcomes of Nutrient-Gene Interactions. Principal Investigator: $150,000.|
|2003-2008||CIHR New Emerging Team - Institute of Gender and Health Sex/Gender Influences on Musculoskeletal Health Across the Lifespan. Co-Investigator: $1,522,540|
To view Raylene A. Reimer's publications please see his Curriculum Vitae (PDF format)
Kristine Lee, Technician
Alannah Maurer, PhD student
Jill Parnell, PhD student
Lindsay Eller, PhD student
Kim Wagner-Jones, MSc student
Kim Pyra, MSc student
Megan Hallam, MSc student
Danielle Reid, MSc student
Gigi Ho, MBT student