GENES and DEVELOPMENT RESEARCH GROUP
Developmental Biology at the University of Calgary
The discovery of new genes and their functions in organisms such as the nematode Caenorhabditis elegans and the fruitfly Drosophila melanogaster, coupled with transgenesis and homologous recombination in mice, has produced the current explosion in our understanding of the most fundamental processes of life. These basic research discoveries are both the targets and the tools for new advances in medicinal chemistry, and are the principle elements from which genetic manipulation in medicine will be developed. Moreover, these model systems will be essential to test the functions of novel classes of developmentally important genes identified in the human genome sequencing project.
The Genes & Development Research Group (GDRG) is a grouping within the Alberta Children's Hospital Research Institute in the Faculty of Medicine. Our common interest is the use of model systems to examine genes that regulate developmental processes in all multicellular animals, from worms to humans. The overall goal of this interdisciplinary group of basic scientists is the establishment of a world-class centre of excellence for innovative research and training in genetics and developmental biology.
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The GDRG occupies approximately 20,000 sq. ft. of contiguous space in the northwest quadrant of the second floor of the Health Sciences Centre, with a blend of individual labs, labs without walls and specialized common facilities (e.g. imaging, reading room, etc.). Our objective is to provide investigators and trainees with first class molecular and cellular biology research facilities and the most highly interactive environment possible. We believe that such an approach will allow the greatest realization of productive collaborations, intellectually stimulating interactions and comprehensive training for our students, our postdoctoral fellows and for ourselves.